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JIB321 - Biochemistry
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INSTRUCTION
INTRODUCTION
Course Introduction
Learning Teaching & Assessment Plans
Main Reference
Ice-Breaking
Netiquette
ANNOUNCEMENT
WEBEX
ATTENDANCE
RECORDING
WEBEX 1 RECORDING 28/10/2024
WEBEX 2 RECORDING 02/12/2024
WEBEX 3 RECORDING 06/01/2025
WEBEX 4 RECORDING 21/01/2025
WEBEX 5 INTENSIVE RECORDING 06/03/2025
WEBEX 6 INTENSIVE RECORDING 06/03/2025
WEBEX 7 RECORDING 25/03/2025
WEBEX 8 RECORDING 14/04/2025
WEBEX 9 RECORDING 19/05/2025
WEBEX 10 RECORDING 23/06/2025
COURSE WORK
QUIZ 2 JIB321 AS2024/2025
Assignment
Assignment AS 2024/2025
Steps on Setting Up Bechling Account
Steps on Downloading and Installing UCSF Chimera
Steps on Downloading and Installing Biovia Discovery Studio Visualizer
Tips/Guidelines for answering Q1
Tips/Guidelines for answering Q3
Tips/Guidelines for answering Q4
Assignment Submission
Quiz
Quiz 1 (10%) Date: 03/01/2025 Time: 9.00 pm - 10.00 pm
MANUAL (LABORATORY WORK)
JIB321 Lab and Report
Table of Practical
Interactive Book of Protein and Phosphate Determination by Spectrophotometer (Physical / Lab 1)
Practical Report Lab 1 (New)
Explanation for JIB321 Lab 2 (Online)
Interactive Book of Enzyme Activity (Online / Lab 2)
Tables for Online Lab 2
Practical Report Online Lab 2
Explanation for JIB321 Lab 3 (Virtual)
Interactive Book of Factors Affecting Enzyme Activity (Virtual / Lab 3)
Tables for Virtual Lab 3
Practical Report Virtual Lab 3
Electron Transport Chain
Interactive Book of Electron Transport Chain (Physical / Lab 4)
Practical Report Lab 4 (ET)
TOPIC 1: Biochemistry Organization
Introduction
Additional Learning Materials
Biochemistry, Organisation of Cells, & Water Note
The Laws of Thermodynamic, Entropy and Gibbs Free Energy
Different between Eukaryotic and Prokaryotic Cells
Summary
Key Term
References
Main Learning Materials
Self-learning Activities
Organisation of Living Things
Self Assessment
Organisation of Living Things
Additional Materials
Main Learning Materials
Self Learning Activity
The differences between prokaryotes and eukaryotes
Self Assessment
Prokaryotic cells vs Eukaryotic cells
Additional Materials
Main Learning Materials
Self Learning Activity
Water Polarity
Self Assessment
Water as solvent
TOPIC 2: Amino Acids & Peptide
Introduction
Additional Learning Materials
Amino Acids & Peptide Note
Classification of amino acids
Peptide bond: Formation and Cleavage
Oligo-basic amino acids, potential nicotinic acetylcholine receptor inhibitors
Summary
Key Terms
References
Main Learning Materials
Self-Learning Activities
Amino acids
Self Assessment
Amino acids
Titration Curve and pI Calculation
Main Learning Materials
Self-Learning Activities
Peptide
Self Assessment
Peptide
TOPIC 3 : 3D structure of Protein
Introduction
Additional Learning Materials
3D Structure of Protein Note
Four level of protein structure
Hemoglobin and The Bohr Effect
Multiscale MD simulation of wild-type and sickle hemoglobin aggregation
Summary
Key Terms
References
Main Learning Material
Self-Learning Activity
Primary and Secondary
Self Assessment
Primary and Secondary
Main Learning Material
Self-Learning Activity
Tertiary
Self Assessment
Tertiary
Main Learning Material
Self-Learning Activity
Mark the words that compare between myoglobin and haemoglobin
Self Assessment
Myoglobin vs Haemoglobin
TOPIC 4 : Enzyme
Introduction
Additional Educational Resorces
Enzyme NOTE
An Introduction to Enzyme Kinetics
Steady state and The Michaelis Menten
Research on Students’ Understanding of Michaelis-Menten Kinetics and Enzyme Inhibition: Implications for Instruction and Learning
Summary
Key Terms
References
Main Educational Resources
Self-learning Activities
Function of Enzymes
Self-Assessment
Identify enzyme involve in food digesting and describe the mechanism (TLO1)
Main Educational Resources
Self-learning Activities
Enzyme Substrate Binding
Self-Assessment
Lock and key and induced-fit models (TLO2)
Main Educational Resources
Self-learning Activities
Mark the words that compare between Michaelis-Menten and Lineweaver-Burk Plot
Self-Assessment
Enzyme Curve (TLO3)
Main Educational Resources
Self-learning Activities
Competitive, non-competitive, uncompetitive inhibitors
Self-Assessment
Type of Inhibition (TLO4)
TOPIC 5 : Nucleic Acids
Introduction
Additional Learning Materials
Note Nucleic Acid
Nucleotide
Supercoiling
RNA-based therapeutics: an overview and prospectus
Summary
Key Terms
References
Subtopic 1
Main Learning Materials
Self-Learning Activity
Differences between DNA and RNA structure (TLO1)
Self-Assessment
Main Learning Materials
Self-Learning Activity
Elaborate the function of three RNAs involved in transcription and protein synthesis (TLO2)
Self-Assessment
RNA type and function (TLO2)
TOPIC 6 : Carbohydrate
Introduction
Additional Learning Materials
Note Carbohydrate and Metabolism
Carbon Chiral Sugar
Glycogen Metabolism
Gut microbial carbohydrate metabolism contributes to insulin resistance
Fructose Metabolism Step 1
Summary
Key Terms
References
Main Learning Materials
Self-Learning Activity
Self-Assessment
Explain the function of monosaccharide, disaccharide and polysaccharide (TLO1)
Main Learning Materials
Self-Learning Activity
Discuss the location and process of carbohydrate metabolism (TLO2)
Self-Assessment
Carbohydrate Metabolism (TLO2)
Main Learning Materials
Self-Learning Activity
Draw and elaborate the process of gluconeogenesis (TLO3)
Self-Assessment
Gluconeogenesis (TLO3)
TOPIC 7 : Lipid
Introduction
Additional Learning Materials
Lipid & Metabolism NOTE
Structure of Lipids
Beta Oxidation of Fatty acids
The Effect of Trans Fatty Acids on Human Health: Regulation and Consumption Patterns
Summary
Key Terms
References
Subtopic 1
Main Learning Materials
Self-Learning Activity
Self-Assessment
Lipid groups and functions
Main Learning Materials
Self-Learning Activity
Self-Assessment
Lipid metabolism
Main Learning Materials
Self-Learning Activity
Self-Assessment
Energy yield
TOPIC 8 : Glycolysis
Introduction
Additional Learning Materials
Note Glycolysis
Glycolysis Pathway Made Simple
Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Summary
Key Terms
References
Subtopic 1
Main Learning Materials
Self-Learning Activity
Describe the first-phase and second-phase of glucose breakdown (TLO1)
Self-Assessment
Molecules in Glycolysis
Main Learning Materials
Self-Learning Activity
Elaborate between acid lactic fermentation and alcoholic fermentation (TLO2)
Self-Assessment
Glycolysis Phase Comparison
TOPIC 9 : The Citric Acid Cycle
Introduction
Additional Learning Materials
Note TCA cycle
Overview of TCA
Time to say goodbye to the Krebs Cycle
Summary
Key Terms
References
Subtopic 1
Main Learning Materials
Self-Learning Activity
Citric Acid Cycle (TLO1)
Draw the Kreb cycle and explain each steps involved (TLO1)
Self-Assessment
TCA
Main Learning Materials
Self-Learning Activity
Metabolism related to Krebs Cycle (TLO2)
Amino acid metabolism (TLO2)
Self-Assessment
Glyoxylate Cycle
TOPIC 10 : Electron Transport Chain
Introduction
Additional Learning Materials
Note (Electron Transport Chain & Oxidative Phosphorylation)
The Electron Transport Chain Explained (Aerobic Respiration)
Cellular Respiration
Summary
Key Terms
References
Main Learning Materials
Self-Learning Activity
Draw complexes involved in ETC. Explain role for each complex. (TLO1)
Self-Assessment
Organization of ETC (TLO1)
Main Learning Materials
Self-Learning Activity
Discuss the sources of Electron carries (TLO2)
Self-Assessment
Electron Carrier (TLO2)
Main Learning Materials
Self-Learning Activity
ETC & Oxidative Phosphorylation
Self-Assessment
Chemiosmosis / Oxidative Phosphorylation
FEEDBACK
COURSE FILE (OBE AS2022/2023)
COURSE PORTAL FILE
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JIB321 - Biochemistry
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Course info
JIB321 - Biochemistry
Lecturer:
DR. MOHAMMAD TASYRIQ BIN CHE OMAR
Skill Level
:
Beginner
