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JIB322 - Molecular Biology
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INSTRUCTION
INTRODUCTION
Course Introduction
Learning Teaching & Assessment Plan
Main Reference
Ice-Breaking
Netiquette
ANNOUNCEMENT
IMPORTANT INFO
WEBEX
Attendance
Recording
WEBEX 1 Recording 29/10/2024
WEBEX2 Recording 03/12/2024
WEBEX 3 Recording 07/01/2025
WEBEX 4 Recording 22/01/2025
WEBEX 5 - INTENSIVE RECORDING 03/03/2025
WEBEX 6 - INTENSIVE RECORDING 03/03/2025
Assignment
Assignment
PDF 1
PDF 2
PDF 3
Assignment
Quiz
Quiz (20%) Date: 14/01/2025 Time: 9.00 pm - 10.00 pm
MANUAL (LAB WORK)
Practical AS2024/2025
Interactive Book of Physical and Virtual Lab 1
Plasmid file AS2024/2025
Practical Report Lab 1
Interactive Book of Physical and Virtual Lab 2
Practical Report Lab 2
Interactive Book of Virtual Lab 3
Practical Report Virtual Lab 3
Interactive Book of Virtual Lab 4
Practical Report Virtual Lab 4
Gel Image for 8/02/2025
FINAL EXAMINATION
TOPIC 1
Introduction
Additional Learning Materials
Structure of DNA, RNA & Protein Note
DNA History
RNA History
Introduction to Nucleic Acids and Nucleotides
Overview of Protein Structure
The Sequence of Sequencers: The History of Sequencing DNA
Summary
Key Terms
References
Main Learning Materials
Self-learning Activity
The differences between DNA and RNA structure
Self Assessment
DNA vs RNA
Main Learning Materials
Self-learning Activity
The Versatility of RNA
AR tRNA
Self Assessment
The Versatility of RNA Role
Main Learning Materials
Self-learning Activity
Augmented Reality of Protein
Self Assessment
3D of Protein Structure
TOPIC 2
Introduction
Additional Learning Materials
DNA Replication Note
DNA Replication: Introduction
DNA Polymerase Active Site
DNA Polymerase Mistake
DNA Polymerase Proofreading
Summary
Key Terms
References
Main Learning Materials
Self-learning Activities
Drawing Replication Fork
Self Assessment
Main Learning Materials
Self-learning Activities
DNA Polymerase
Self Assessment
DNA Polymerase
Main Learning Materials
Self-learning Activity
DNA replication components
Self Assessment
Components of DNA Replication
TOPIC 3 :
Introduction
Additional Learning Materials
Technique in Molecular and Genome Maintenance NOTE
PCR (Polymerase Chain Reaction)
Human gene structure and scale
Heterochromatin: Guardian of the Genome
Summary
Key Terms
References
Main Learning Materials
Self-learning Activities
Describe four molecular techniques commonly used
Self Assessment
Main Learning Materials
Self-learning Activities
Describe genome size, genome complexity and genome density
Self Assessment
Main Learning Materials
Self-learning Activities
Describe genome compactness in eukaryotes
Self Assessment
TOPIC 4 :
Introduction
Additional Learning Materials
Mutability & Repair NOTE
DNA Repair 2
DNA Repair 1
DNA Damage Repair
Summary
Key Terms
Main Learning Materials
Self-learning Activities
Source / Cause of Mutation
Self Assessment
Cause of mutation
Main Learning Materials
Self-learning Activities
Reversing or Correcting Mutations
Self Assessment
DNA Repair and Tolerance System
TOPIC 5 :
Introduction
Main Learning Materials
Self-learning Activities
Describe two factors initiate the homologous recombination (TLO1)
Draw and compare the homologous recombination in human and bacteria (TLO2)
Self Assessment
Homologous Recombination Mechanism (TLO2)
Additional Learning Materials
Note Homologous Recombination
Genetic recombination 1
Homologous recombination
The Rad52 SSAP superfamily and new insight into homologous recombination
Summary
Key Terms
TOPIC 6 :
Introduction
Main Learning Materials
Self-learning Activities
Describe three class of conservative site-specific recombinations (TLO1)
Discuss the transposition mechanisms in prokaryotic (TLO2)
Self Assessment
Transposon (TLO2)
Additional Learning Materials
Note Conservative Site-Specific Recombination
CONSERVATIVE SITE SPECIFIC RECOMBINATION
CRISPR-based genome editing through the lens of DNA repair
Summary
Key Terms
TOPIC 7 :
Introduction
Main Learning Materials
Self-learning Activities
Explain the steps in transcription process (TLO1)
Discuss three types of RNA splicing (TLO2)
List and describe three main regulatory RNA involved in expression (TLO3)
Self Assessment
Transcription Mechanism (TLO1)
RNA Splicing (TLO2)
Additional Learning Materials
Transcription RNA Splicing RNA Regulators NOTE
Transcription and mRNA processing
Organization and regulation of gene transcription
Summary
Key Terms
TOPIC 8 :
Introduction
Main Learning Materials
Self-learning Activities
Explain about translation steps, please include the diagram (TLO1)
Discuss about Wobble Concept and Codon degenerated (TLO2)
Self Assessment
Translation (TLO1)
Genetic Code (TLO2)
Additional Learning Materials
Note Translation and Genetic Code
Overview of Translation
The Genetic Code
Roadblocks and resolutions in eukaryotic translation
Summary
Key Terms
TOPIC 9 :
Introduction
Main Learning Materials
Self-learning Activities
Explain about regulator and activator (TLO1)
Discuss the RNA polymerase recruitment (TLO2)
Describe about Lysogenic and Lytic propagation (TLO3)
Self Assessment
Transcription Regulation in Prokaryotes (TLO1)
RNA Polymerase Recruitment (TLO2)
Additional Learning Materials
Note Transcription Regulation in Prokaryotes
Regulation of Transcription
Lambda Phage Genome
High-resolution studies of lysis–lysogeny decision-making in bacteriophage lambda
Summary
Key Terms
TOPIC 10 :
Introduction
Main Learning Materials
Self-learning Activities
Explain the function of enhancer, insulator, and repressor (TLO1)
Discuss the binding between activator and enhancer (TLO2)
Describe the role of nucleosome in transcription regulation (TLO3)
Self Assessment
Transcription Regulation in Eukaryotes (TLO1)
Binding between regulator and gene (TLO2)
Additional Learning Materials
Lecture Note (Transcription Regulation in Eukaryotic)
Transcriptional Regulation in Eukaryotes
Chromatin Organization and Nucleosome Structure
Regulation of chromatin by histone modifications
Summary
Key Terms
FEEDBACK
COURSE FILE (OBE AS2022/2023)
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Ijazah Sarjana Muda Sastera (Kepujian)
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Bidang Kesusasteraan
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Ijazah Sarjana Muda Sains Kemasyarakatan (Kepujian)
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JIB322 - Molecular Biology
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Course info
JIB322 - Molecular Biology
Lecturer:
DR. MOHAMMAD TASYRIQ BIN CHE OMAR
Skill Level
:
Beginner
